.Best Nootropics of 2024: Brain Booster Supplements for Improving Cognition

Sponsored content by Fitliving

Poor cognition and mental fatigue can be more than just frustrating—they can seriously impact your daily performance and overall quality of life. This is where nootropics, often referred to as “brain boosters,” come into play.

These supplements are popular among students and professionals. They are also popular among everyday people looking to enhance their mental clarity, memory, focus, and overall cognitive function. But do nootropics really work? And even if they do, how do you find the best one for your needs?

To clear up the confusion, we’ve thoroughly reviewed 13 of the best nootropics available in 2024, starting with TakeThesis. Our goal is to provide you with clear, detailed insights so you can find a nootropic that suits your specific cognitive needs and lifestyle.

Best Nootropic Supplements 

  1. TakeThesis—Best nootropic overall 
  2. Noocube—Best for studying
  3. Hunter Focus—Best for focus
  4. Addall XR—Best for convenience 
  5. ONNIT Alpha Brain—Best for neurotransmitter support
  6. MindLab Pro—Best for vegans
  7. FOCL Day—Best for social anxiety
  8. Performance Lab Mind—Best for motor function 
  9. MindVitality—Best for energy
  10. Neuro Gum—Best chewable nootropic
  11. Brain Pill—Best for cellular protection 
  12. BetterBrand—Best for affordability 
  13. Earth & Star Mushroom Gummies—Most gentle nootropic

The best nootropics combine evidence-based ingredients to create a supplement with a broad range of benefits. They also offer great value for money and are highly rated in customer reviews. TakeThesis is our overall winner, with Noocube at a close second.

1. TakeThesis—Best Nootropic Overall



  • Six different blends with their own sets of benefits 
  • Personalized coaching 
  • Provides evidence to back up their range of ingredients
  • Offers starter kits to help customize your blends


  • The starter kit may not give you enough time to see each supplement’s benefit 

Who is TakeThesis Best For?

TakeThesis takes the top position as the best nootropics overall. It includes six different supplements with a wide range of evidence-based ingredients.

TakeThesis Benefits

Thesis Nootropics blends are Clarity, Confidence, Creativity, Energy, Logic, and Motivation. Their names match their claimed benefits. Let’s take a closer look at the benefits of the key ingredients in each blend:

  • Clarity: Alpha-GPC may support healthy cognitive function, contributing to improved focus, better memory recall, and overall mental sharpness. 
  • Energy: Teacrine plays a crucial role in this blend by boosting not just physical energy, but also mental alertness and motivation. It’s known for providing a sustained energy lift without the jittery side effects commonly associated with caffeine [1]. 
  • Motivation: In the Motivation blend, CDT (Dynamine) is key for enhancing cognitive control and improving reaction times during mentally demanding tasks.
  • Confidence: Zembrin may help in elevating mood, reducing anxiety, and promoting a positive mental state, which is essential for building confidence.
  • Logic: Synapsa is the star ingredient here, renowned for its ability to improve working memory. It could also aid in processing information more efficiently, enhancing reasoning skills, and supporting complex cognitive functions. 
  • Creativity: KSM-66 Ashwagandha in this blend is pivotal for reducing stress and anxiety, which are often barriers to creative thinking. 

That said, TakeThesis also offers a free 10-minute session with certified coaches, providing personalized guidance to help you align the Thesis blends with your goals.


TakeThesis costs $79 per month with a subscription or $119 for a one-time purchase.


Each daily dose consists of two to four pills, depending on the formula. You can choose one formula in the morning and another in the evening if necessary.


  • Alpha-GPC
  • Teacrine
  • CDT (Dynamine)
  • Zembrin
  • Synapsa
  • KSM-66 Ashwagandha


TakeThesis provides a degree of personalization to finding the best nootropics online. With six blends and online coaching, it’s not one-size-fits-all.

>>Check the best deals for TakeThesis here 

2. Noocube—Best for Studying



  • Includes carotenoids that may benefit eye and brain health
  • Caffeine-free formula 
  • Free shipping worldwide
  • 60-day money-back guarantee


  • Dopamine-boosting ingredients may have an additive effect with ADHD meds


Noocube takes our award for the best nootropic for studying. Its blend of ingredients may benefit brain and eye health, a winning combination for long hours at a computer or reading books.

Noocube Benefits

Noocube’s ingredients work by providing antioxidant support and aiding the production of energy and neurotransmitters such as dopamine.

Its most unique inclusion is Lutemax, a blend of three carotenoids. One of these, lutein, may boost cognition and reduce eye strain caused by bright light exposure. Lutein is more concentrated in the brain than any other carotenoid. Research demonstrates that it can improve verbal skills, memory, and processing speed [2].


1 bottle of Noocube costs $64.99. The best value deal is $194.99 for 5 bottles. 


Take two Noocube capsules every day, preferably in the morning. 


  • Vitamins B1, B7 (biotin) and B12
  • Bacopa monnieri
  • Ashwagandha
  • Pterostilbene
  • Cat’s claw
  • Panax ginseng
  • L-theanine
  • Choline
  • Lutemax
  • Resveratrol
  • Tyrosine


Noocube contains ingredients that may improve learning, memory, and visual function over time. These benefits make it one of the best nootropics for studying.

>>Check the best deals for Noocube here 

3. Hunter Focus—Best Nootropics for Focus

Hunter Focus


  • Boosts the production of neurotransmitters such as GABA and dopamine 
  • Some ingredients may promote healthy circulation 
  • Antioxidants for cellular protection 


  • Caffeine may be overstimulating for some people 

Who is Hunter Focus Best For?

Hunter Focus shines as one of the best nootropics for enhancing focus. We recommend it if you can’t seem to concentrate even when you otherwise enjoy what you are doing or if you need to get things done ASAP.

Hunter Focus Benefits 

Hunter Focus contains many ingredients that may improve attention, mood, and cellular health with its antioxidant and circulatory-stimulating properties.

Phosphatidylserine is one ingredient that can boost focus. A trial involving children with ADHD found that phosphatidylserine significantly improved symptom scores, especially in inattention. While average DSM-IV scores fell from 11.4 to 7.2, inattention scores on another measurement dropped by 90 percent, from 1.0 to 0.1 [3].


The best value deal for Hunter Focus is the 4-bottle package for $270. 


Take six capsules of Hunter Focus every day. 


  • Concentration activation: L-tyrosine, Ginkgo biloba, l-theanine, Spanish sage, Citicoline
  • Memory matrix: Lion’s mane, maritime pine bark extract, Bacopa monnieri, Rhodiola rosea
  • Mood amplification: Phosphatidylserine, ashwagandha root, caffeine, Panax ginseng, acetyl-l-carnitine
  • Vitamins B6, B9, B12, C, D3, and K2 


Hunter Focus can clear the fog of an impaired attention span while lifting mood. 

>>Check the best deals for Hunter Focus here 

4. Addall XR—Best for Convenience

Addall xr


  • Choose between capsules and a liquid shot 
  • Includes both stimulating and calming ingredients 
  • Shots provide a quick energy lift 


  • Ingredients are in a proprietary blend 

Who is Addall XR Best For? 

Addall XR tops our list as one of the best nootropics to take, and you can choose between the slower-onset capsules or the more rapid-onset liquid shot.

Addall XR Benefits

Addall XR contains key B vitamins for cellular energy and neurotransmitter production. This is how it can give you a short-term boost. 

Vitamins B1, B2, and B6 are all necessary for specific steps of cellular energy production pathways. As this process happens in a cycle, one missed nutrient can disrupt the entire pathway. Additionally, vitamin B1 is required for brain cell growth and maintenance [4]. 


One bottle of Addall XR costs $99, or you can save 7 percent with a subscription. Each shot costs $6, or $5.52, with a subscription. 


Take three capsules of Addall XR per day, or one serving of the liquid shot. 


  • Bacopa monnieri 
  • GABA
  • Vitamins B1, B2, and B6 


Addall XR may conveniently boost your short-term cognitive health by supporting energy production and regulating neurotransmitter levels. It comes in capsules for slower release and a liquid shot for fast results.

>>Check the best deals for Addall XR here 

5. ONNIT Alpha Brain—Best for Neurotransmitter Support

ONNIT Alpha Brain


  • May support a range of neurotransmitters
  • Can have a relaxing effect 
  • Save with a subscription 


  • Contains a very high dose of vitamin B6

Who is ONNIT Alpha Brain Best For?

Consider Alpha Brain if you want one of the best nootropics for overall neurotransmitter support. It may be what you’re looking for if you’re studying or in a high-stakes profession.

ONNIT Alpha Brain Benefits 

ONNIT Alpha Brain may support several neurotransmitters, including acetylcholine, the main player in cognition. Through this and other benefits, its alpha-GPC content is shown to improve cognitive performance and related functional outcomes [5]. 


A one-off purchase costs $79.95 for 45 days, but you can save 15 percent with a subscription.


Take two capsules of Alpha Brain every day. 



  • L-theanine
  • Phosphatidylserine 
  • Alpha GPC
  • Huperzia serrata extract 
  • Vitamin B6 


Support your healthy brain chemistry with ONNIT Alpha Brain, which may offer great all-around assistance. This includes promoting cognitive functions like memory, mental speed, and focus.

>>Check the best deals for ONNIT Alpha Brain 

6. MindLab Pro—Best for Evidence 

Mind Lab Pro


  • Vegan-friendly formula
  • Key B vitamins for brain function 
  • Antioxidants for cellular protection 


  • High doses of vitamin B6 may be harmful to people of smaller body weights.

Who is MindLab Pro Best For? 

We recommend MindLab Pro to vegans with high performance demands, whether mental or physical. 

MindLab Pro Benefits 

Clinical studies show that MindLab Pro may benefit memory and reaction times, including both simple (SRT) and choice reaction times (CRT). SRT involved responding to one stimulus, while CRT required a response involving one of eight choices. This could benefit athletes in team and extreme outdoor sports, where rapid psychomotor responses and decision-making are necessary [6]. 


A 4-month package costs $207.00, while 1 month costs $69.00. 


Take two to four capsules of Mind Lab Pro every day. 


  • Citicoline 
  • Bacopa monnieri
  • Lion’s mane mushroom 
  • Phosphatidylserine 
  • N-acetyl-l-tyrosine 
  • L-theanine
  • Rhodiola rosea
  • Maritime pine bark extract
  • Vitamins B6, B9, and B12 


Mind Lab Pro is evidence-backed as a complete formula, unlike most other products where each ingredient has been tested alone. Plus, it is among the best nootropics for vegans looking to boost their cognitive function.

>>Check the best deals for Mind Lab Pro here

7. FOCL Day—Best for Social Anxiety



  • Combat fatigue and relieve stress 
  • Subscription offers available 
  • Made to FDA standards 


  • High doses of vitamin B6 may be harmful to some people

Who is FOCL Day Best For?

FOCL Day is one of the best nootropics if you struggle with social anxiety, a situation that some of its ingredients have been tested under.

FOCL Day Benefits

Some ingredients in FOCL Day, including L-theanine (green tea extract) and rhodiola, may improve cognitive function in stressful situations. Research demonstrates an increase in calming brain waves even when volunteers were shown images that would otherwise trigger social stress [7]. This may mean less freezing up in everyday life, and reduced stress.


FOCL Day costs $49 as a one-time purchase or $39.20 per month as a subscription. 


Take two capsules daily. 


  • Lion’s mane 
  • Bacopa monnieri
  • Rhodiola rosea 
  • L-theanine
  • Vitamin B6 


Fight social anxiety with FOCL Day, which may improve performance under stress. The supplement is also designed to reduce fatigue and energize you throughout the day.

>>Check the best deals for FOCL Day 

8. Performance Lab Mind—Best for Motor Function 

Performance Lab Mind


  • Pine bark extract offers antioxidant properties
  • Caffeine-free formula
  • Convenient dose


  • May interact with ADHD meds 

Who is Performance Lab Mind Best For?

Performance Lab Mind contains several potent ingredients that we recommend as one of the best nootropics for improving physical performance.

Performance Lab Mind Benefits

Performance Lab Mind may support psychomotor performance, focus, and cellular health. A trial involving 75 young men found that citicoline, one of its ingredients, significantly improved psychomotor speed and attention. Psychomotor speed is critical for sports such as football or outdoor activities such as surfing, where you must respond quickly [8].


The 4-month package costs $177.00, while 1 month costs $59. 


Just take one capsule every day on an empty stomach. 


  • Citicoline 
  • Phosphatidylserine 
  • L-tyrosine
  • Maritime pine bark extract 


Performance Lab Mind may boost your athletic abilities by supporting your brain’s ability to communicate with your muscles. It also includes antioxidants that are believed to play a role in promoting recovery after prolonged physical activity.

>>Check the best deals for Performance Lab Mind here 

9. MindVitality—Best for Energy

Mind Vitality


  • May relieve stress and promote relaxation 
  • Can support healthy energy metabolism 
  • 100-day money-back guarantee


  • Dopamine boosters may negatively interact with ADHD medication

Who is MindVitality Best For?

If you’re feeling mentally and physically sluggish, MindVitality may be the best nootropic for you.

MindVitality Benefits

MindVitality contains several ingredients that could enhance mental and physical performance by boosting dopamine and energy production. One, Panax ginseng, increases the counts of mitochondria in your cells through mechanisms such as its antioxidant effect. The mitochondria generate almost all of your energy [9].


5 month’s supply is $209.99, while just 1 month costs $69.99. 


Take three tablets with breakfast or lunch. 


  • Stress Kill Switch: Ashwagandha, Rhodiola rosea, Panax ginseng, phosphatidylserine
  • Brain Focus: Bacopa monnieri, mucuna, Ginkgo biloba, pine extract 
  • Cognitive Accelerators: Huperzia serrate, lion’s mane, n-acetyl-l-tyrosine


For a sustained energy boost, MindVitality could be one of the best nootropics for you. It may also help enhance mental performance so you absorb more of what you learn and remain productive all day.

>>Check the best deals for MindVitality 

10. Neuro Gum—Best Chewable Nootropic

Neuro Gum


  • Choose between peppermint and cinnamon flavor
  • Vitamins B6 and B12 may boost red blood cell production 
  • Subscription options available 


  • Contains caffeine 

Who is Neuro Gum Best For?

Neuro Gum Energy & Focus tops our list of the best nootropics for people who don’t like swallowing pills.

Neuro Gum Benefits

Neuro Gum may give you a short-term boost to your cognitive function. A study on theanine and caffeine, both alone and in combination, found that they can support reaction time and attention span. Cognitive and neuron activity tests were used [10].


A pack of 72 mints or 54 gum pieces costs $38.00. You can also subscribe to save 10 percent. 


One daily dose consists of two gum or mint pieces. 


  • Caffeine
  • L-theanine
  • Vitamin B6 
  • Vitamin B12 


For rapid relief of a cloudy mind, consider Neuro Gum’s Energy & Focus convenient nootropic formulation. It is formulated with L-theanine, natural caffeine, and B vitamins to improve your focus and mental endurance.

>>Check the best deals for Neuro Gum 

11. Brain Pill—Best for Cellular Protection 



  • DHA for brain cell structure and function 
  • Vinpocetine may protect brain cells 
  • May support key neurotransmitter production 


  • May negatively interact with pharmaceutical dopamine boosters

Who is Brain Pill Best For?

Brain Pill contains an extensive spread of ingredients that may place it among the best nootropics for brain cell protection

Brain Pill Benefits

One of Brain Pills’ unique ingredients that could support its cellular protective properties is vinpocetine. Vinpocetine, a substance from periwinkles, may help to protect the energy-producing parts of your cells from damage [11]. 


Brain Pill usually costs $79.95 for one month, but discounts are often available. 


Take two capsules of Brain Pill every day. 


  • Vitamins B5, B6, B9, and B12 
  • Citicoline
  • Bacopa monnieri
  • L-tyrosine
  • Phosphatidylserine 
  • Ginkgo biloba
  • DHA omega-3 complex
  • L-theanine
  • Huperzia serrata
  • Vinpocetine 


Brain Pill may protect your brain cells during periods of stress by supporting their energy-producing centers. This benefit may lead to better short and long-term memory and improved mental performance under stress.

>>Check the best deals for Brain Pill

12. BetterBrand—Best for Affordability 

Better Brand


  • Affordable chewable gummies
  • May reduce stress hormone production 
  • Phosphatidylserine for focus


  • Does not include essential vitamins 

Who is BetterBrand Best For?

BetterBrand BetterMushrooms is one of the best nootropics if you’re on a budget, with its range of energizing antioxidants.

BetterBrand Benefits

A key benefit of BetterMushrooms is to help you clear your head by reducing stress. Research on ashwagandha, one of its ingredients, shows that the herb can significantly relieve perceived stress and stress hormones. Both physical and mental symptoms of stress were reduced [12]. 


A one-time purchase of BetterMushrooms costs you $39.95 for 1 month, and you can save further with a subscription.


Take 2 gummies daily. 


  • Ashwagandha
  • Rhodiola rosea
  • Pinus pinaster
  • Phosphatidylserine 
  • Schisandra


Soothe stress for your mind, body, and wallet with BetterBrand BetterMushrooms. It’s among the best nootropics for improving focus, memory, and cognitive function.

>>Check the best deals for BetterBrand

13. Earth & Star Mushroom Gummies—Most Gentle Nootropic

Earth & Star


  • No overpowering dopamine boosters
  • Lion’s mane for nerve cells
  • Pleasant raspberry flavor 


  • Only available in one flavor

Who is Earth & Star Mushroom Gummies Best For?

Earth & Star Mushroom Gummies are one of the best nootropics for people who are sensitive to caffeine or strong dopamine-boosting stimulants.

Earth & Star Mushroom Gummies Benefits

Some of these mushroom gummies’ benefits are gradual and long-term. Lion’s mane, one of its two ingredients, can increase nerve growth factor, which is required for the growth of new brain cells and maintaining existing ones. Meanwhile, L-theanine can enhance reaction times and attention [13]. 


At $32 for 30 servings with a subscription, this is one of the more affordable nootropics.


Chew two gummies every day. 


  • Lion’s mane
  • L-theanine 


With Earth & Star Mushroom Gummies, you can enjoy short and long-term benefits without being overstimulated. It may help improve memory, boost concentration, support cognitive function, and reduce morning fatigue.

>>Check the best deals for Earth & Star Mushroom Gummies 

What Are Nootropics?

Nootropics are a category of supplements, both natural and pharmaceutical that are designed to enhance cognitive function. These substances are believed to potentially improve memory, increase focus and attention, promote creativity, and support overall brain health. 

How Do Nootropics Work?

Nootropics work by altering the availability of the brain’s supply of neurochemicals, including neurotransmitters, enzymes, and hormones. This helps improve the brain’s oxygen supply or stimulate nerve growth.

They enhance cognitive functions such as memory, creativity, motivation, and attention. The mechanisms of action can vary depending on the specific nootropic. Some work by increasing the production of neurotransmitters like dopamine and serotonin, which improve mood and focus.

Meanwhile, others may enhance brain function by improving blood flow to the brain, thereby increasing alertness and concentration.

>>Check the best deals for TakeThesis here 

Benefits of Nootropic Supplements

The best nootropic supplements may have a range of benefits for your cognitive and emotional health.

Alleviating Depression Symptoms

Through supporting the production of neurotransmitters such as dopamine, GABA, acetylcholine, and serotonin, some ingredients may help to lift mood.

Increasing Energy Levels

Most of the best nootropics support cellular energy production, an essential benefit as your brain is the most energy-demanding organ.

Improving Focus, Concentration, and Memory

Another significant advantage of using the best nootropic supplements is their ability to improve focus and attention span. Ingredients like L-Theanine and Alpha GPC have been found to enhance concentration and promote mental clarity.

Enhancing Creativity

Besides improving focus, stimulating dopamine-boosting supplements can also keep you engaged and support creativity.

The Science Behind The Best Nootropics

The best nootropics share some common ingredients, as they have the largest bodies of evidence.


This is a precursor to key neurotransmitters: dopamine, norepinephrine, and epinephrine. In the brain, L-Dopa is converted into dopamine, which plays a major role in mood, motivation, and attention. Its supplementation is thought to enhance cognitive functions, particularly in conditions associated with dopamine deficiency.

Ginkgo Biloba

Ginkgo Biloba is known for its ability to improve blood circulation to the brain. It is believed to enhance brain function by increasing oxygen and nutrient supply to brain cells. It’s also associated with improvements in memory and cognitive speed and may have neuroprotective properties [14].

Omega-3 Fatty Acids

These essential fatty acids, particularly those found in fish oil, are crucial for brain health. They play a vital role in maintaining the fluidity of cell membranes and are involved in various brain processes, including neurotransmitter production. Omega-3 fatty acids are linked to improved cognitive function, mood stabilization, and neuroprotection [15].

>>Check the best deals for TakeThesis here 

Rhodiola Rosea

This adaptogen herb helps the body adapt to stress and combat fatigue. Rhodiola is believed to improve cognitive functions by balancing neurotransmitters in the brain and enhancing stress resistance. It’s often used to boost concentration, memory, and mental stamina under stressful conditions.

What to Consider When Choosing a Nootropic Supplement?

When choosing the best nootropic for you, it’s most important to consider ingredient safety and efficacy. Here, we chose the best nootropic supplements that only feature evidence-backed nutrients and herbal extracts. We also recommend taking affordability and factors such as money-back guarantees into account.

Are Nootropic Pills Safe?

Most of the best nootropics are well-tolerated for most people. Some ingredients may be overstimulating, such as caffeine. However, you must also read every ingredient list to check for allergies.

Who Should Try a Nootropic?

The best nootropic supplements may be beneficial for various groups of people, but it’s essential to consider individual health, goals, and circumstances:

  • Students and Academics: People seeking enhanced focus, memory, and learning capabilities for studying or academic research may benefit from the best nootropics.
  • Professionals: Those in high-pressure, competitive work environments may use nootropics to improve concentration, cognitive stamina, and stress resilience.
  • Athletes: Some athletes might use the best nootropics to enhance mental clarity, reaction times, and focus during training and competitions.
  • Aging Individuals: Older adults might seek nootropics to support memory, cognitive function, and neuroprotection.
  • People with Cognitive Impairments: Under medical supervision, some nootropics may be used to address cognitive issues related to conditions like ADHD or brain fog.
  • Creatives: Those in creative fields may use nootropics to enhance creativity, thought clarity, and motivation.

>>Check the best deals for TakeThesis here 

Who Should Avoid Nootropics?

Certain individuals should exercise caution or avoid any of the best nootropics altogether:

  • Pregnant and Breastfeeding Women: The effects of many nootropics on fetal and infant development are not well understood. It’s safer for women who are pregnant or breastfeeding to avoid them.
  • Children and Adolescents: The brains of young people are still developing, and the long-term effects of the best nootropic supplements on this development are unclear.
  • Individuals with a History of Substance Abuse: Some of the best nootropic supplements, especially those with stimulant properties, might pose a risk for individuals with a history of substance abuse.
  • People with Mental Health Disorders: Individuals with mental health issues, particularly anxiety or mood disorders, should be cautious as some nootropics might exacerbate these conditions.

Alternatives to Nootropic Supplements

Alternatives to the best nootropic supplements for enhancing cognitive function, particularly in areas like anxiety, depression, and overall brain health, include a range of approaches:


While the best nootropics focus on cognitive enhancement, there are other supplements that can support brain health and emotional well-being:

  • Omega-3 Fatty Acids: Essential for brain function and mood regulation.
  • Vitamin B Complex: Plays a key role in brain health and emotional balance.
  • Magnesium: Known for its calming effects helpful in managing stress and anxiety.

For Anxiety and Depression

Alternative natural treatments can be effective in managing symptoms of anxiety and depression without relying on the best nootropic supplements:

  • Herbal Remedies: Herbs like St. John’s Wort, Ashwagandha, and Lavender are often used for their natural anxiolytic and antidepressant properties.
  • Mindfulness and Meditation: Regular practice can significantly reduce symptoms of anxiety and depression.
  • Exercise: Certain types of exercise, including rhythmic and repetitive activities like jumping jacks, can induce a state of relaxation, reducing muscle tension and promoting a sense of calm.

Lifestyle Changes

Simple changes in daily habits and routines can have a profound impact on mental health and cognitive function:

  • Diet: A diet rich in fruits, vegetables, lean proteins, and whole grains can improve brain function and mood.
  • Sleep: Ensuring adequate and quality sleep is crucial for mental health and cognitive function.
  • Social Interaction: Engaging in social activities can improve mood and cognitive health.
  • Reducing Alcohol and Quitting Smoking: These lifestyle changes are important for mental and cognitive health.

See a Doctor

For persistent or severe symptoms of cognitive decline, anxiety, or depression, professional medical advice is essential:

  • Professional Evaluation: A healthcare provider can assess your symptoms and recommend appropriate treatments. This may include therapy or prescription medications.
  • Cognitive Behavioral Therapy (CBT): This is a highly effective treatment for anxiety and depression.
  • Medications: For some, prescription medications may be necessary to manage symptoms of anxiety and depression.

>>Check the best deals for TakeThesis here 

How We Evaluated Nootropics

We researched ingredient effectiveness and safety alongside value for money when finding the best nootropics.


First of all, the ingredients in the best nootropics have to be effective in boosting cognition. We prioritized human trials over animal research.


Additionally, each ingredient in the best nootropic supplements had to be safe at the included doses. No pharmaceutical contaminants, which are more likely to have side effects, were permitted.


Chances are you will need the best nootropic supplements for several months or even indefinitely. That’s why we only chose products that cost less than $3 per day.


Continuous daily use of a supplement also requires convenience. For this reason, we ensured each product was meant to be taken at convenient times and a dose of just a few pills.


Here are the most common questions people ask when searching for the best nootropics. 

What Is the #1 Rated Nootropic?

Each person has different needs, so we rate TakeThesis as the #1 option among the best nootropic supplements we reviewed because of its more individualized approach.

Is It Worth Taking Nootropics?

The best nootropics feature evidence-backed ingredients, so they are likely to give you some cognitive benefit. 

Do Nootropics Work for ADHD?

Some ingredients in the best nootropics for ADHD may have some potential to manage the symptoms by enhancing focus and cognitive function. However, their effectiveness can vary greatly, and they are not a substitute for clinically approved ADHD treatments.

Is Adderall Considered a Nootropic?

Adderall counts as a nootropic because it can boost cognition. However, it’s unsafe and illegal without a prescription.

How Soon Will I See Cognitive Improvements After Using Nootropics?

While some of the best nootropics can take days or weeks to show their full effects, others may give you a short-term boost in a few hours.

Can Nootropics Be Used as a Pre-workout?

Some of the best nootropic supplements, like those containing caffeine, may be effective pre-workouts. They can improve psychomotor performance and energy production.

Final Thoughts

The best nootropics cover a wide range of benefits relevant to you with evidence-based ingredients. These typically center around increasing energy and neurotransmitter production, but one brand stood out thanks to its individualized approach.

Overall, the top nootropic brand we found was TakeThesis. With six supplemental formulas, you can mix and match them to find your winning combination.

While the best nootropics can be beneficial, it’s crucial to choose one that aligns with your specific cognitive needs and lifestyle.

>>Check the best deals for TakeThesis here 


  1. Cesareo, Kyle R., et al. “The Effects of a Caffeine-like Supplement, TeaCrine®, on Muscular Strength, Endurance and Power Performance in Resistance-Trained Men.” Journal of the International Society of Sports Nutrition, vol. 16, no. 1, 2019, p. 47, doi:10.1186/s12970-019-0316-5.
  2. Stringham, James M et al. “Lutein across the Lifespan: From Childhood Cognitive Performance to the Aging Eye and Brain.” Current developments in nutrition vol. 3,7 nzz066. 4 Jun. 2019, doi:10.1093/cdn/nzz066
  3. Hirayama, S et al. “The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial.” Journal of human nutrition and dietetics : the official journal of the British Dietetic Association vol. 27 Suppl 2 (2014): 284-91. doi:10.1111/jhn.12090
  4. Tardy, Anne-Laure et al. “Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence.” Nutrients vol. 12,1 228. 16 Jan. 2020, doi:10.3390/nu12010228
  5. Sagaro, Getu Gamo et al. “Activity of Choline Alphoscerate on Adult-Onset Cognitive Dysfunctions: A Systematic Review and Meta-Analysis.” Journal of Alzheimer’s disease : JAD vol. 92,1 (2023): 59-70. doi:10.3233/JAD-221189
  6. Utley, Andrea. “The Efficacy of A Nootropic Supplement on Information Processing in Adults: A Double Blind, Placebo Controlled Study.” Biomedical Journal of Scientific & Technical Research, vol. 49, no. 1, 2023, doi:10.26717/bjstr.2023.49.007746.
  7. Boyle, Neil Bernard et al. “A Combination of Green Tea, Rhodiola, Magnesium, and B Vitamins Increases Electroencephalogram Theta Activity During Attentional Task Performance Under Conditions of Induced Social Stress.” Frontiers in nutrition vol. 9 935001. 22 Jul. 2022, doi:10.3389/fnut.2022.935001
  8. McGlade, Erin et al. “The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent Males.” Journal of attention disorders vol. 23,2 (2019): 121-134. doi:10.1177/1087054715593633
  9. Jung, Dong-Hyuk et al. “Effects of ginseng on peripheral blood mitochondrial DNA copy number and hormones in men with metabolic syndrome: A randomized clinical and pilot study.” Complementary therapies in medicine vol. 24 (2016): 40-6. doi:10.1016/j.ctim.2015.12.001
  10. Kahathuduwa, Chanaka N et al. “Acute effects of theanine, caffeine and theanine-caffeine combination on attention.” Nutritional neuroscience vol. 20,6 (2017): 369-377. doi:10.1080/1028415X.2016.1144845
  11. Svab, Gergely et al. “The Mitochondrial Targets of Neuroprotective Drug Vinpocetine on Primary Neuron Cultures, Brain Capillary Endothelial Cells, Synaptosomes, and Brain Mitochondria.” Neurochemical research vol. 44,10 (2019): 2435-2447. doi:10.1007/s11064-019-02871-9
  12. Chandrasekhar, K et al. “A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.” Indian journal of psychological medicine vol. 34,3 (2012): 255-62. doi:10.4103/0253-7176.106022
  13. Lai, Puei-Lene, et al. “Neurotrophic Properties of the Lion’s Mane Medicinal Mushroom, Hericium Erinaceus (Higher Basidiomycetes) from Malaysia.” International Journal of Medicinal Mushrooms, vol. 15, no. 6, 2013, pp. 539–554, doi:10.1615/intjmedmushr.v15.i6.30.
  14. Kandiah, Nagaendran et al. “Treatment of dementia and mild cognitive impairment with or without cerebrovascular disease: Expert consensus on the use of Ginkgo biloba extract, EGb 761®.” CNS neuroscience & therapeutics vol. 25,2 (2019): 288-298. doi:10.1111/cns.13095
  15. Bazan, Nicolas G. “Cellular and molecular events mediated by docosahexaenoic acid-derived neuroprotectin D1 signaling in photoreceptor cell survival and brain protection.” Prostaglandins, leukotrienes, and essential fatty acids vol. 81,2-3 (2009): 205-11. doi:10.1016/j.plefa.2009.05.024
East Bay Express E-edition East Bay Express E-edition
music in the park san jose